Chemistry Department Chair and Professor Owen McDougal, with biomolecular sciences doctoral candidate Matthew Turner and chemistry graduate students Paul Phillips and Leanna Marquart, co-authored a recently published article in the open access journal Toxins.
An excerpt from the abstract begins: “Nicotinicacetylcholine receptors (nAChRs) are found throughout the mammalian body and have been studied extensively because of their implication in a myriad of diseases. α-Conotoxins (α-CTxs) are peptide neurotoxins found in the venom of marine snails of genus Conus. α-CTxs are potent and selective antagonists for a variety of nAChR isoforms.”
To read the article, click here: Mutagenesis of α-Conotoxins for Enhancing Activity and Selectivity for Nicotinic Acetylcholine Receptors