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Publications

Original Research Articles

(bold name = NTM personnel, * = corresponding author)

Yu CY, Mannen EM, Lujan TJ, Uzer G, Upasani V, Edmonds EW, *Fitzpatrick CK. (2024). Porcine computational modeling to investigate developmental dysplasia of the hip. Journal of Orthopaedic Research.

DQ Nesbitt, X Pu, MW Turner, AG Zavala, L Bond, *TJ Lujan. (2024). Age‐dependent changes in collagen crosslinks reduce the mechanical toughness of human meniscus. Journal of Orthopaedic Research.

Henderson BS, Cudworth KF, Peña E, *Lujan TJ. (2023). Modeling fatigue failure in soft tissue using a visco-hyperelastic model with discontinuous damage. Journal of the Mechanical Behavior of Biomedical Materials, 144(1), 105968.

Nesbitt DQ, Burruel DE, Henderson BS, *Lujan TJ. (2023). Finite element modeling of meniscal tears using continuum damage mechanics and digital image correlation.  Scientific Reports, 10;13(1):4039.

Benfield KJ, Burruel DE, *Lujan TJ. (2023). Guidelines for Accurate Multi-Temporal Model Registration of 3D Scanned Objects. Journal of Imaging, 9(2), 43.

Nesbitt DQ, Nelson ML, Shannon KS, *Lujan TJ. (2023). Dots-on-plots: A web application to analyze stress–strain curves from tensile tests of soft tissue. Journal of Biomechanical Engineering, 145(2): 024504.

Benfield KJ, Pinkley ZA, Burruel DE, Lewis KJ, Ferguson DS, *Lujan TJ. (2022). In vitro method to quantify and visualize mechanical wear in human meniscus subjected to joint loading. Journal of Mechanical Behavior of Biomedical Materials, 133:105338.

Henderson BS, Cudworth KF, Wale ME, Siegel DN, *Lujan TJ. (2022). Tensile fatigue strength and endurance limit of human meniscus. Journal of Mechanical Behavior of Biomedical Materials, 127: 105057.

Nesbitt DQ, Siegel DN, Nelson SJ, *Lujan TJ. (2021). Effect of age on the failure properties of human meniscus: High-speed strain mapping of tissue tears. Journal of Biomechanics, 115:110126.

Wale ME, Nesbitt DQ, Henderson BS, Fitzpatrick CK, Creechley JJ, *Lujan TJ. (2021). Applying ASTM Standards to Tensile Tests of Musculoskeletal Soft Tissue: Methods to Reduce Grip Failures and Promote Reproducibility. Journal of Biomechanical Engineering, 143(1):011011.

Nelson SJ, Creechley JJ, Wale ME, *Lujan TJ. (2020). Print-A-Punch: A 3D printed device to cut dumbbell-shaped specimens from soft tissue for tensile testing. Journal of Biomechanics, 112:110011.

*Oxford JT, Cornell KA, Romero JJ, Smith DB, Yarnell TL, Wood RM, Jorcyk CL, Lujan TJ, Albig AR, Mitchell KA, McDougal OM, Fologea D, Estrada D, Tinker JK, Nagarajan R, Warner DL, Rohn TT, Browning J, Beard RS Jr, Warner LR, Morrison BE, Fitzpatrick CK, Uzer G, Bond L, Frahs SM, Keller-Peck C, Pu X, Woodbury LG, Turner MW. (2020). Center of Biomedical Research Excellence in Matrix Biology: Building Research Infrastructure, Supporting Young Researchers, and Fostering Collaboration. International Journal of Molecular Sciences, 21(6):2141.

*Thurston JH, Clifford AJ, Henderson BS, Smith TR, Quintana D, Cudworth KF, Lujan TJ, Cornell KA. (2020). Development of Photoactive g-C3N4/Poly(vinyl alcohol) Composite Hydrogel Films with Antimicrobial and Antibiofilm Activity. ACS Applied Bio Materials, 3(3):1681-1689.

Frahs SM, Reeck JC, Yocham KM, Frederiksen A, Fujimoto K, Scott CM, Beard RS Jr, Brown RJ, Lujan TJ, Solov’yov IA, Estrada D, *Oxford JT. (2019). Prechondrogenic ATDC5 Cell Attachment and Differentiation on Graphene Foam; Modulation by Surface Functionalization with Fibronectin. ACS Applied Mater Interfaces, 11(45):41906-41924.

Yocham KM, Scott C, Fujimoto K, Brown R, Tanasse E, Oxford JT, Lujan TJ, *Estrada D. (2018). Mechanical Properties of Graphene Foam and Graphene Foam – Tissue Composites. Advanced Engineering Materials, 1800166.

Frahs SM, Oxford JT, Neumann EE, Brown RJ, Keller-Peck CR, Pu X, *Lujan TJ. (2018). Extracellular matrix expression and production in fibroblast-collagen gels: Towards an in vitro model for ligament wound healing. Annals of Biomedical Engineering, 1-14.

Warburton KJ, Everingham JB, Helms JL, Kazanovicz AJ, Hollar KA, Brourman JD, Fox SM, *Lujan TJ. (2018). Wear Testing of a Canine Hip Resurfacing Implant That Uses Highly Cross-linked Polyethylene. Journal of Orthopaedic Research, 36(4), 1196-1205.

Hollar KA, Ferguson DS, Everingham JB, Helms JL,*Lujan TJ. (2018). Quantifying wear depth in hip prostheses using a 3D optical scanner. Wear, 394-395, 195-202.

Stender CJ, Rust E, Martin PT, Neumann EE, Brown RJ, *Lujan TJ. (2017). Modeling the effect of collagen fibril organization on ligament mechanical behavior. Biomechanics and Modeling in Mechanobiology, 17(2), 543-57.

Creechley JJ, Krentz ME, *Lujan TJ. (2016). Fatigue Life of Bovine Meniscus under Longitudinal and Transverse Tensile Loading. Journal of Mechanical Behavior of Biomedical Materials, 69, 185-192.

Lamb CL, Cholico GN, Perkins DE, Fewkes MT, Oxford JT, Lujan TJ, Morrill EE, *Mitchell KA. (2016). Aryl Hydrocarbon Receptor Activation by TCDD Modulates Expression of Extracellular Matrix Remodeling Genes during Experimental Liver Fibrosis. BioMed Research International, 5309328.

Morrill EE, Tulepbergenov A N, Stender CJ, Lamichhane R, Brown RJ, *Lujan TJ. (2016). A validated software application to measure fiber organization in soft tissue. Biomechanics and Modeling in Mechanobiology, 15(6), 1467-78.

Lack W, Elkins J, Lujan TJ, Peindl R, Kellan J, Anderson DD, *Marsh JL. (2016). Motion Predicts Clinical Callus Formation: Construct-Specific Finite Element Analysis of Supracondylar Femur Fractures. Journal of Bone and Joint Surgery, 98(4):276-284.

Porter SM, Dailey HL, Hollar KA, Klein K, Harty JA, *Lujan TJ. (2016). Automated measurement of fracture callus in radiographs using portable software. Journal of Orthopaedic Research, 34(7):1224-33.

*Augat P, Morgan EF, Lujan TJ, MacGillivray TJ, Cheung WH. (2014). Imaging Techniques for the Assessment of Fracture Repair. International Journal of the Care of the Injured, 45:16-22.

*Bottlang M, Doornink J, Lujan TJ, Fitzpatrick DC, Madey SM. (2012). Biomechanics and Use of Far Cortical Locking in Orthopaedic Trauma. Orthopaedic Knowledge Online.

Bahney CS, Lujan TJ, Hsu CW, Bottlang M, West JL, *Johnstone B. (2011). Visible Light Photoinitiation of Mesenchymal Stem Cell-Laden Bioresponsive Hydrogels. European Cells and Matrix, 22:43-55.

*Henderson CE, Lujan TJ, Bottlang M, Fitzpatrick DC, Marsh JL. (2011). Healing of Distal Femur Fractures Treated with Locked Plates. Clinical Orthopaedics and Related Research, 469(6):1757-65.

*Lujan TJ, Wirtz, Madey SM, Bottlang M. (2011). A Novel Bioreactor for the Dynamic Stimulation and Mechanical Evaluation of Multiple Tissue-Engineered Constructs. Tissue Eng Part C Methods, 17(3):367-74.

*Bottlang M., Doornink J, Lujan TJ, Fitzpatrick DC, Marsh JL, Augat P, Rechenberg B, Lesser M, Madey SM. (2010). Effects of Construct Stiffness on Healing of Fractures Stabilized with Locking Plates. Journal of Bone and Joint Surgery (Am), 2:12-22.

*Henderson CE, Lujan TJ, Bottlang M, Fitzpatrick DC, Marsh JL. (2010). Stabilization of distal femur fractures with IM nails and locking plates: differences in callus formation. Iowa Journal of Orthopaedics, 30:61-8.

Lujan TJ, Henderson CE, Madey SM, Fitzpatrick DC, Marsh JL, *Bottlang M. (2010). Locked Plating of Distal Femur Fractures Leads to Inconsistent and Asymmetrical Callus Formation: Journal of Orthopaedic Trauma, 24(3): 156-62.

*Lujan TJ, Madey SM, Fitzpatrick DC, Byrd GD, Sanderson JM, Bottlang M. (2010). A Computational Technique to Measure Fracture Callus in Radiographs. Journal of Biomechanics, 43(4): 792-5

Lujan TJ, Underwood CJ, Jacobs N, *Weiss JA. (2009). Contribution of glycosaminoglycans to viscoelastic tensile behavior of human ligament. Journal of Applied Physiology, 106(2): 423-31

Lujan TJ, Dalton MS, Thompson BM, Ellis BJ, *Weiss JA. (2007). Effect of ACL Deficiency on MCL strains and joint kinematics. Journal of Biomechanical Engineering, 129(3):386-92.

Lujan TJ, Underwood CJ, Henninger HB, Thompson BM, *Weiss JA. (2007). Effect of dermatan sulfate glycosaminoglycans on the quasi-static material properties of the human medial collateral ligament. Journal of Orthopaedic Research, 25(7):894-903.

Ellis BJ, Lujan TJ, Dalton MS, *Weiss JA. (2006). MCL insertion site and contact forces in the ACL-Deficient knee. Journal of Orthopaedic Research, 24(4):800-810.

*Weiss JA, Gardiner JC, Ellis BJ, Lujan TJ, Phatak NS. (2005). Three-dimensional finite element modeling of ligaments: Technical aspects. Medical Engineering and Physics, 27(10):845-61.

Lujan TJ, Lake SP, Plaizier TA, Ellis BJ, *Weiss JA. (2005). Simultaneous measurement of three-dimensional joint kinematics and tissue strains with optical methods. ASME Journal of Biomechanical Engineering, 127:193-197.

Conference Proceedings

Lujan TJ, Wirtz K, Madey SM, Bottlang M: High-Throughput Mechanical Evaluation of Tissue Engineered Constructs During Incubation. Accepted, 2011 Annual Meeting of the Orthopaedic Research Society, Jan. 2011 (Podium).

Lujan TJ, Wirtz K, Madey SM, Bottlang M: A bioreactor to mechanically stimulate and evaluate tissue-engineered constructs during culture. Biomedical Engineering Society Conference Annual Meeting, May 2010 (Poster).

Doornink J, Madey SM, Fitzpatrick DC, Lujan TJ, Bottlang M: Analysis of periosteal callus formation in locked plating of distal femur fractures. Accepted, 56th Annual Meeting of the Orthopaedic Research Society, March 2010.

Lujan TJ, Henderson CE, Madey SM, Fitzpatrick DC, Marsh JL, Bottlang M: Factors that Influence Callus Formation in Locked Plating of Distal Femur Fractures. Accepted, Academy of Orthopaedic Surgeons, February 2010 (Poster).

Bottlang M, Doornink J, Lujan TJ, Fitzpatrick D, Madey: Far-cortical locking of distal femur fractures. Accepted, American Academy of Orthopaedic Surgeons, February 2010 (Scientific Exhibit).

Bottlang M, Lujan TJ, Phelan D, Henderson CE, Marsh JL, Fitzpatrick DC, Madey SM: Stabilization of distal femur fractures with IM nails and locking plates: differences in callus formation. Accepted, Orthopaedic Trauma Association, January 2010 (Poster).

Lujan TJ, Henderson CE, O’Donovan M, Madey SM, Fitzpatrick DC, Bottlang M: Automated measurement of callus formation. ASME Summer Bioengineering Conference, June 2009 (Poster).

Lujan TJ, Underwood CJ, Jacobs NT, Weiss JA: Contribution of glycosaminoglycans to the viscoelastic tensile behavior of human ligament. 54th Annual Meeting of the Orthopaedic Research Society, February 2008 (Podium).

Lujan TJ, Underwood CJ, Jacobs NT, Weiss JA: Tissue swelling during extended material testing of ligaments. ASME 2007 Summer Bioengineering Conference, June 2007 (Poster).

Underwood CJ, Lujan TJ, Henninger HB, Weiss JA: The Distribution and Influence of Dermatan Sulfate in Ligament Biomechanics. 5th World Congress of Biomechanics, August 2006 (Podium).

Lujan TJ, Ellis BJ, Thompson BM, Weiss JA: MCL Mechanics in the ACL-Deficient Knee. An experimental and finite element based study. 5th World Congress of Biomechanics, August 2006 (Podium).

Henninger HB, Lujan TJ, Underwood CJ, *Weiss JA: Distribution and mechanical implications of dermatan sulfate in human medial collateral ligament. ASME Summer Bioengineering Conference, June 2006 (Poster).

Underwood CJ, Henninger HB, Lujan TJ, Weiss JA: Glycosaminoglycan concentration and species in human knee ligaments. 52nd Annual Meeting of the Orthopaedic Research Society, February 2006 (Poster).

Lujan TJ, Underwood CJ, Henninger HB, Weiss JA: Dermatan Sulfate glycosaminoglycans do not contribute to the shear or tensile material behavior of the human MCL. 52nd Annual Meeting of the Orthopaedic Research Society, February 2006.

Lujan TJ, Thompson BM, Ellis BJ, Weiss JA: Effect of ACL transection on MCL strains during anterior tibial translation and valgus rotation. 1st Annual Mountain West Biomedical Engineering Conference, August 2005 (Poster).

Henninger HJ, Underwood CJ, Lujan TJ, Weiss JA: Decorin proteoglycans do not resist shear deformation in ligament. Biomedical Engineering Society Conference Annual Meeting, October 2005 (Poster).

Ellis BJ, Dalton MS, Lujan TJ, Weiss JA: Subject-specific finite element modeling of MCL mechanics in the ACL-deficient knee. Proc ASME Summer Bioengineering Conference, June 2005 (Podium).

Dalton MS, Ellis BJ, Lujan TJ, Weiss JA: MCL insertion site and contact forces in the ACL-deficient knee. Proc 51st Annual Orthopaedic Research Society Meeting, 30:814, 2005.

Lujan TJ, Dalton MS, Lake SP, Ellis BJ, Rosenberg TD, Weiss, JA: ACL injury alters MCL strain during anterior-posterior but not varus-valgus loading. Proc 50th Annual Orthopaedic Research Society Meeting, 29:1272, 2004 (Poster).