Dr. Konrad Meister (BMOL Faculty) recently published in PNAS on the Functional aggregation of cell-free proteins enables fungal ice nucleation. Dr. Meister along with his collaborators demonstrated that small extracellular proteins, of which over a hundred are capable of assembling in cell-free environments, make up the fungal ice nucleators that enable ice formation at warm temperatures. Their findings highlight that nature uses a common strategy, E pluribus unum (out of many, one), to enable high subzero ice nucleation temperatures by assembly of ice-nucleating proteins into large functional aggregates.