Julia Oxford, PhD

Education

Doctor of Philosophy, Biochemistry and Biophysics – 1986
Washington State University, Pullman, WA
Dissertation: “Export of Protein in Escherichia coli”
Advisor: Prof. Linda L. Randall
Department of Biochemistry and Biophysics
Washington State University

Master of Sciences, Biochemistry and Biophysics – 1985
Washington State University, Pullman, WA

Bachelor of Arts, Chemistry and Biology (cum Laude) – 1981
Linfield College, McMinnville, OR

Positions Held

• Associate Chair, Department of Biological Sciences, 2014-present
• Professor, Department of Biological Sciences, Boise State University, 2008-present
• Affiliate Faculty, University of Washington, School of Medicine, Department of Biochemistry, 2003-2010
• Affiliate Faculty, University of Idaho, Dept of Microbiology, Molecular Biology and Biochemistry, 2002-2011
• Associate Professor, Department of Biology, Boise State University, 2003-2008
• Assistant Professor, Biology, Boise State University, 2000-2003
  Affiliate Faculty, Oregon Health Sciences University, School of Dentistry, 2000-2002
• Research Assistant Professor, Integrative Biosciences Department (formerly Oral Molecular Biology), School of Dentistry, and Biochemistry and Molecular Biology, School of Medicine, Oregon Health Sciences University, 1995-2000
• Visiting Assistant Professor of Clinical Sciences, Equine Orthopaedics, Colorado State University, 1996-1998
• Senior Research Associate, Shriners Hospital for Crippled Children, Portland, 1992-1996
• Postdoctoral fellow, Shriners Hospital for Crippled Children and Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, 1988-1992
• Postdoctoral fellow, Biochemistry/Biophysics Program, Washington State University, 1988
• Postdoctoral fellow, Dept of Cellular Biology, Swiss Institute for Experimental Cancer Research, 1987-1988
• Graduate Research Assistant, Department of Biochemistry/Biophysics, Washington State University, 1981-1986

Honors and Awards

• Glenn King Fellowship, Chemistry Dept. Washington State University, 1981-1982 ISREC Postdoctoral Fellowship, 1987 and 1988
• Arthritis Investigator Award, Arthritis Foundation, 1996 Gerlinger Research Foundation Award, 1999
• Oregon Medical Research Foundation Award, 2000
• Boise State University Foundation Scholar Award, Research and Creative Activity, 2006 Lori and Duane Steuckle Dean’s Distinguished Faculty Award, 2005-2009
• MMACHS Distinguished Lecture Series February 10, 2011 Boise State University Distinguished Professor 2011-present Stueckle Endowed Chair in Biology, 2017-present
• Top Ten Scholar Honored Faculty Member, 2018

Research Publications

Refereed Publications — Citations: >3010; h-index: 28; i10 index: 50 1985 -2007 available upon request

* Student authors

36. Gerritsen M,* Oxford JT, Frary M, Henderson J,* Hampikian JM. (2008) Immuno-SEM characterization of developing bovine Materials Science and Engineering: C, 28:341-346.
37. Kahler R*, Yingst S,* Krawczak D*, Oxford J, and Westendorf (2008) Collagen 11a1 is indirectly activated by Lymphocyte Enhancer-binding factor 1 (Lef1) and negatively regulates osteoblast maturation. Matrix Biology, 27(4):330-8. PMCID: PMC2431459.
38. Bowen KB,* Reimers AP,* Luman S,* Kronz JD, Fyffe WE, Oxford JT. (2008) Immunohistochemical localization of collagen type XI alpha 1 and alpha 2 chains in human colon Journal of Histochemistry and Cytochemistry, 56:275-283. PMCID: PMC2324180.
39. Halsted KC,* Bowen KB,* Bond L, Jorcyk CJ, FyffeWE, Kronz JD, Oxford JT. (2008) Collagen XI α1 in normal and malignant breast tissue. Modern Pathology. 21:1246-54. PMC2586035.
40. Takata T, Oxford JT, Demeler B*, and Lampi (2008) Deamidation destabilizes and triggers aggregation of a lens protein, A3-crystallin. Protein Science. 17:1565-75. PMCID: PMC2525517.
41. Yingst S,* Cole J,* Warner L,* Bloxham K,* Brown R, Kenoyer L, Knowlton B, Oxford JRT. (2009) Characterization of Collagenous Matrix Assembly in a Chondrocyte Model Journal of Biomedical Materials Science, 90:247-55. PMC2842207.
42. Toumpoulis IK, Oxford JT, Cowan DB, Anagnostopoulos CE, Rokkas CK, Chamogeorgakis TP, Angouras DC, Shemin RJ, Navab M, Ericsson M, Federman M, Levitsky S, McCully (2009) Differential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms. Ann Thorac Surg. 88:506-13. PMC2834780.
43. Fang M,* Adams JS,* McMahan BL,* Brown RJ, Oxford JT. (2010) The expression patterns of minor fibrillar collagens during development in zebrafish. Gene Expr Patterns, Oct-Dec;10(7- 8):315-22. Epub 2010 Jul 18, PMC2956583.
44. Gorski JP, Huffman NT, Chittur S, Midura RJ, Black C, Oxford J, Seidah (2011) Inhibition of SKI-1 proprotein convertase and caspase-3 blocks transcription of key extracellular matrix genes regulating osteoblastic mineralization. J Biol Chem. 286(3): 1836-49.
45. Tawara K*, Oxford JT, Jorcyk (2011) Clinical significance of interleukin (IL)-6 in cancer metastasis to bone: potential of anti-IL-6 therapies. Cancer Management Research, 2011;3:177-89. Epub 2011 May 18. PMC3101113.
46. Brown R, Mallory C*, McDougal OM, Oxford JT. (2011) Proteomic analysis of Col11a1-associated protein PROTEOMICS, 11(24):4660-76. PMC3463621.
47. Mallory C,* McDougal OM, Oxford JT. (2011) Collagen Type XI alpha-1 Chain Amino Propeptide Structural Model and Glycosaminoglycan Interactions in Silico, in Proceedings of 2011 International Conference on Bioinformatics & Computational Biology (ISBN #: 1-60132-172- 4/CSREA), Editors: Hamid Arabnia and Quoc-Nam Tran, pp.: 632-635, Las Vegas, USA.
48. McDougal OM, Mallory C,* Warner LR,* Oxford JT. (2011) Predicted structure and binding motifs of alpha 1 (XI) collagen. JBio, (GSTF International Journal of BioScience), 1:43-48.
49. Fang M,* Jacob R,* McDougal O, Oxford JT., (2012) Minor fibrillar collagens, variable regions alternative splicing, intrinsic disorder, and tyrosine Protein Cell. Jun;3(6):419-33. PMC3484837.
50. Shea KG, Jacobs JC,* Carey JL, Anderson AF. Oxford JT. (2013) Osteochondritis Dissecans Knee Histology Studies Have Variable Findings and Theories of Etiology, Clinical Orthopaedics and Related Research, Apr;471(4):1127-36.
51. Berger JM,* Rohn TT, Oxford JT. (2013) Autism as the Early Closure of a Neuroplastic Critical Period Normally Seen in Adolescence. Biol Syst. August 20, 1. doi:10.4172/2329-6577.1000118.
52. Bullock C,* Cornia N, Jacob R*, Remm A*, Peavey T*, Weekes K*, Mallory C*, Oxford JT, McDougal OM, Andersen (2013) DockoMatic 2.0: high throughput inverse virtual screening and homology modeling. J Chem Inf Model. Aug 26;53(8):2161-70. doi: 10.1021/ci400047w. Epub 2013 Aug 8. PMC3916141.
53. McDougal OM, Cornia N, Sambasivarao SV, Remm A*, Mallory C*, Oxford JT, Maupin CM, Andersen (2014) Homology modeling and molecular docking for the science curriculum. Biochem Mol Biol Educ. Mar;42(2):179-82. doi: 10.1002/bmb.20767. Epub 2013 Dec 20. PubMed PMID: 24376157.
54. Mikelonis D,* Jorcyk CL, Tawara K*, Oxford JT. (2014) Stüve-Wiedemann syndrome: LIFR and associated cytokines in clinical course and etiology. Orphanet J Rare Dis. Mar 12;9(1):34. doi: 10.1186/1750-1172-9-34. PMC3995696.
55. Hughes AN,* Oxford JT. (2014) A lipid-rich gestational diet predisposes offspring to nonalcoholic fatty liver disease: a potential sequence of Hepatic Medicine: Evidence and Research. Mar 6; 6:15-23. PMC3953741.
56. Bates JT*, Jacobs JC*, Jr, Shea KG, Oxford JT. (2014) Emerging genetic basis of osteochondritis dissecans. Sports Med. 33(2):199-220. PMC3976886.
57. Jacobs JC* Jr, Shea KG, Oxford JT, Carey (2014) Fluoroquinolone use in a child associated with development of osteochondritis dissecans. BMJ Case Rep. Sep 16. pii: bcr2014204544. doi: 10.1136/bcr-2014-204544. PMC4166236.
58. Mellor LF, Baker TL*, Brown RJ, Catlin LW*, Oxford JT. (2014) Optimal 3D culture of primary articular chondrocytes for use in the rotating wall vessel (2014) Aviat Space Environ Med. Aug;85(8):798-804. doi: 10.3357/ASEM.3905.2014. PMCID: PMC4207436.
59. Ryan RE, Martin B*, Mellor L, Jacob RB*, Tawara K*, McDougal OM, Oxford JT, Jorcyk (2015) Oncostatin M binds to extracellular matrix in a bioactive conformation: implications for inflammation and metastasis. Cytokine. 2015 Mar;72(1):71-85.
60. Goyden J*, Tawara K*, Hedeen D*, Willey JS, Oxford JT, Jorcyk (2015) The Effect of OSM on MS3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation. PLoS One. 1;10(6):e0127230. doi: 10.1371/journal.pone.0127230. eCollection 2015.
61. Pu X, Oxford J (2015) Proteomic analysis of tissue engineered cartilage. Cartilage Tissue Engineering; Methods in Molecular Biology. 1340:263-78. doi: 10.1007/978-1-4939-2938-2_19.
62. Parker H*, Conway E*, Goldsberry J*, Jeffries S*, Price E*, Oxford JT. (2015) Genetic and Molecular Aspects of DiGeorge (2015) BIOS. Vol. 86(2): 109-117. doi: 10.1893/0005-3155-86.2.109.
63. Hafez A*, Squires R*, Pedracini A*, Joshi A, Seegmiller RE, Oxford JT. (2015) Col11a1 Regulates Bone Microarchitecture during Embryonic J Dev Biol. 2015;3(4):158-176. Epub 2015 Dec 16. PMCID: PMC4711924.
64. Lamb CL*, Cholico GN*, Perkins DE*, Fewkes MT*, Oxford JT, Lujan TJ, Morrill EE*, Mitchell (2016) Aryl Hydrocarbon Receptor Activation by TCDD Modulates Expression of Extracellular Matrix Remodeling Genes during Experimental Liver Fibrosis. Biomed Res Int. 2016;2016:5309328. Epub 2016 Sep 8. PMCID: PMC5031815.
65. Oxford AE*, Jorcyk CL, Oxford JT. (2016) Neuropathies of Stüve-Wiedemann Syndrome due to mutations in leukemia inhibitory factor receptor (LIFR) gene. J Neurol Neuromedicine. 2016;1(7):37-44. PMCID:
66. Hughes A*, Oxford AE*, Tawara K*, Jorcyk CL, Oxford JT. (2017) Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Int J Mol Sci. 2017 Mar 20;18(3). pii: E665. doi: 10.3390/ ijms18030665. PMCID: PMC5372677.
67. Robertson JC*, Jorcyk CL, Oxford JT. (2018) DICER1 Syndrome: DICER1 Mutations in Rare Cancers (Basel). 2018 May 15;10(5). pii: E143. doi: 10.3390/ cancers10050143. PMCID: PMC5977116.
68. FrahsSM*, Oxford JT, Neumann EE*, Brown RJ, Keller-Peck CR, Pu X, Lujan (2018) Extracellular Matrix Expression and Production in Fibroblast-Collagen Gels: Towards an In Vitro Model for Ligament Wound Healing. Ann Biomed Eng. 2018 Jun 5. doi: 10.1007/s10439-018-2064-0. [Epub ahead of print] PubMed PMID: 29873012.
69. Yocham KM*, Scott C, Fujimoto K* Brown R, Tanasse E*, Oxford JT, Lujan TJ, Estrada (2018)Mechanical Properties of Graphene Foam and Graphene Foam – Tissue Composites, Advanced Engineering Materials. 2018 DOI: 10.1002/adem.201800166.
70. Frahs SM*, Reeck JC*, Yocham KM*, Frederiksen A, Fujimoto K*, Scott CM, Beard RS, Brown R, Lujan TJ, Solov’yov IA, Estrada D, Oxford JT. (2019) Prechondrogenic ATDC5 cell attachment and differentiation on graphene foam; modulation by surface functionalization with fibronectin. ACS Appl Mater Interfaces. Oct 22. doi: 10.1021/acsami.9b14670.
71. Covert H*, Mellor LF, Wolf CL*, Ankenbrandt N*, Emathinger JM, Tawara K*, Oxford JT, Jorcyk CL. (2019) OSM-induced CD44 contributes to breast cancer metastatic potential through cell detachment but not epithelial-mesenchymal transition. Cancer Manag Res. Aug 15;11:7721-7737
72. Touchstone H*, Bryd R, Loisate S, Thompson M, Kim S, Puranam K, Senthilnathan AN, Pu X, Beard R, Rubin J, Alwood J, Oxford JT, Uzer G. (2019) Recovery of stem cell proliferation by low intensity vibration under simulated microgravity requires LINC complex. NPJ Microgravity. May 15;5:11. doi: 10.1038/s41526-019-0072-5.
73. Oxford JT, Reeck JC, Hardy MJ*. (2019) Extracellular Matrix in Development and Disease. Int J Mol Sci. Jan 8;20(1). pii: E205. doi: 10.3390/ijms20010205.
74. Beard RS, Jr, Hoettels BA*, Meegan JE, Wertz TS*, Cha BJ, Yang X, Oxford JT, Wu MH, Yuan SY. (2020). AKT2 maintains brain endothelial claudin-5 expression and selective activation of IR/AKT2/FOXO1-signaling reverses barrier dysfunction. Journal of Cerebral Blood Flow and Metabolism., 40(2), 374–391.
75. Mellor LF, Nordberg RC*, Huebner P, Mohiti-Asli M, Taylor MA, Efird W, Oxford JT, Spang JT, Shirwaiker RA, Loboa EG. (2020). Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering applications. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 108(5), 2017–2030.
76. Cornell KA, Benfield K*, Berntsen T*, Clingerman J*, Croteau A*, Goering S*, Moyer D*, Provost M*, White A*, Plumlee D, Oxford JT, Browning J. (2020). A Cold Atmospheric Pressure Plasma Discharge Device Exerts Antimicrobial Effects. Int J Latest Trends Eng Technol. 2020;15(3):036‐
77. Oxford JT, Cornell KA, Romero JJ, et al. (2020) Center of Biomedical Research Excellence in Matrix Biology: Building Research Infrastructure, Supporting Young Researchers, and Fostering Collaboration. Special Issue: Extracellular Matrix in Development and Disease 2.0 in Int J Mol Sci. 2020;21(6):2141. Published 2020 Mar 20. doi:10.3390/ ijms21062141.
78. Tanikella AS*, Hardy MJ*, Frahs SM*, Cormier AG*, Gibbons KD*, Fitzpatrick CK, Oxford JT. Emerging Gene-Editing Modalities for Osteoarthritis. Int J Mol Sci. 2020 Aug 22;21(17):6046. doi: 10.3390/ijms21176046. PMID: 32842631; PMCID: PMC7504272.
79. Hardy MJ*, Reeck JC*, Fang M*, Adams JS*, Oxford JT. Col11a1a Expression Is Required for Zebrafish Development. J Dev Biol. 2020 Aug 28;8(3):16. doi: 10.3390/jdb8030016. PMID: 32872105; PMCID: PMC7558312.
80. Bas G*, Loisate S*, Hudon SF*, Woods K*, Hayden EJ, Pu X, Beard R, Oxford JT, Uzer G. Low Intensity Vibrations Augment Mesenchymal Stem Cell Proliferation and Differentiation Capacity during in vitro Expansion. Sci Rep. 2020 Jun 10;10(1):9369. doi: 10.1038/s41598-020-66055-0. PMID: 32523117; PMCID: PMC7286897.
81. Oxford JT, Jorcyk CL. Students engage in primary literature in molecular biology techniques using an online journal club format. Biochem Mol Biol Educ. 2020 Oct 20. doi: 10.1002/bmb.21472. Epub ahead of print. PMID: 33080662.

Invited Lectures and Presentations: > 70 presentations from 1983 – present; available upon request Contributed papers and posters at professional meetings: > 250 conference papers and posters from 1990 to present; available upon request

Research Funding

TITLE: Center of Biomedical Research Excellence in Matrix Biology DURATION: 8/1/14 to 5/31/24

FUNDING SOURCE: NIH/NIGMS

ROLE ON PROJECT: Principal Investigator, Program Director

TOTAL AWARD: $20 M

TITLE: Gateway Scholarships in Biological Sciences NSF #1644233 DURATION: 02/15/17 to 02/14/22

FUNDING SOURCE: National Science Foundation

ROLE ON PROJECT: Principal Investigator

TOTAL AWARD: $1,000,000

TITLE: Idaho INBRE Program

DURATION: 7/15/04 to 6/31/24

FUNDING SOURCE: NIH (NIGMS) P20GM103408 subaward (PI: Bohach)

ROLE ON PROJECT: Boise State University PI, Steering committee member

TOTAL AWARD: $2.6 M to Boise State University for INBRE 1, $4.1 M for INBRE 2, $443,751 for ARRA supplement, and $868,750 for INBRE 3, $955,000 for INBRE 4 Block grant and Alteration/Renovation

TITLE: Replicating Marrow Mechanics of Stem Cells Ex vivo

DURATION: 3/07/18 to 6/06/21

FUNDING SOURCE: National Institutes of Health (federal flow-through from University of Pittsburg) P2CHD086843 subaward 126873-13 (PI: Uzer)

ROLE ON PROJECT: Co-I

Previous funding:

1. Topoisomerase II and the regulation of gene expression by higher-ordered chromatin structure. 1/1987-12/1988, Postdoctoral fellowship, Funded by ISREC, Swiss Institute for Experimental Cancer Research, SF 45,000.
2. Cartilage Matrix Proteins. 1989-1995, Postdoctoral Fellowship, Funded by Shriners Hospital.
3. The role of type XI collagen in the functional integrity of normal and osteoarthritic cartilage. 7/1996 – 6/1999, Principal Investigator, Funded by Arthritis Foundation, Biomedical Science Grant, $225,000.
4. Biological resurfacing of large articular cartilage defects. 7/1996- 6/1998 Co-Investigator, (P.I. C.W. McIlwraith) Funded by Steadman-Hawkins Sports Medicine Foundation and National Football League Charities (NFL) $60,000.
5. Application of a small sample extraction technique and quantitative polymerase chain reaction in the analysis of mRNA, DNA and protein from normal and osteoarthritic equine articular cartilage. 7/1996-6/1997 Co-Investigator, (P.I. Gayle Trotter) Funded by CSU College Research Council, $9,400.
6. Synovial fluid and tissue expression of degradative enzymes, inflammatory mediators and cytokines in naturally occurring joint disease in horses. 7/1997-6/1998 Co-Investigator, (P.I. Gayle Trotter) Funded by CSU Research Council, $34,000.
7. Synovial fluid and tissue expression of degradative enzymes, inflammatory mediators and cytokines in naturally occurring joint disease in horses—equipment. 9/1997, Co-Investigator, (P.I. Gayle Trotter) Funded by Southern California Equine Foundation, $11,095.
8. The treatment of osteoarthritis in exercised horses using interleukin-1 receptor antagonist delivered using gene therapy. 1/1998 Principal Investigator, Funded by Southern California Equine Foundation, $49,306.
9. Collagen Type XI in skeletal development and disease. 2/1999, Principal Investigator, Funded by Gerlinger Foundation, $24,988.
10. X-ray diffraction studies of protein structures. 1998, Collaborator (P.I. Oren Anderson) Funded by Research Corporation, $25,000.
11. Type XI collagen in extracellular matrix assembly. 3/1/2000 – 2/28/2001 Principal Investigator, MRF, OHSU, $25,000.
12. Biomedical Optics for Medical Research and Clinical Care. 6/1/2000 – 5/31/2005, NIH, Investigator (P.I. Steven Jacques) $3,115,625 total, of which $210,000 is designated for “Biomechanical and Optomechanical characterization of laboratory-generated cartilage” subproject-JTO).
13. NSF-EPSCOR Acquisition of a peptide synthesizer. 2002, $15,000.
14. NSF MRI/RUI Acquisition of an EPR Spectrometer for Collaborative Research and Materials Science Education. 09/01/03 – 08/31/06, $338,795.
15. Biomedical Research Infrastructure Network for Idaho, 10/1/2001- 6/30/2004, NIH Co-Investigator (Michael Laskowski, P.I.), $6,000,000 total of which $1,383,947 was designated for BSU.
16. Supplement to Biomedical research infrastructure Network for Idaho, $2,000,000 total, of which $496,583 designated for BSU.
17. MSMRI Role of MeCP2 in neuronal cell differentiation and Rett syndrome. 6/2003-5/2004, $5,000.
18. Molecular regulation of bone density and trabecular structure. 10/2005 – 6/2006, NASA Idaho EPSCoR, $4000.
19. NSF MRI/RUI Acquisition of a Transmission Electron Microscope for Multidisciplinary Research and Education. 09/01/05 – 08/31/07, Co-P.I., $691,910.
20. Collaborative Grant Improvement Initiative. 07/01/05 – 06/30/07, Boise State University, Principal Investigator, $150,000.
21. Investigating the role of collagen type XI in the structural integrity of cartilage tissue. 03/15/05 – 03/14/07, NASA Idaho Space Grant consortium, Principal Investigator, $30,000.
22. Type XI collagen isoforms in skeletal biology. 2/1/2001 – 1/31/2008, NIH RO1, Principal Investigator, $1,349,811.
23. Type XI collagen isoforms in skeletal biology-Independent Scientist Award. Career Development Grant. 9/1/2002 – 8/31/2007, NIH, Principal Investigator, $385,516.
24. NSF MRI/RUI: Acquisition of a Confocal Microscope for Multidisciplinary Research & Education. 09/01/06 – 08/31/10, NSF, Principal Investigator, $348,000.
25. J. Murdock Charitable Trust, Investigating mechanisms of alcohol-induced liver fibrosis using a zebrafish model system. (P.I. Kristen Mitchell), 5/17/10 – 12/31/11, Collaborator, $15,000.
26. Musculoskeletal Research Center. 07/01/07 – 06/30/11, Idaho State Board of Education, HERC, Principal Investigator, $1,000,000.
27. Acquisition of a Liquid Chromatography – Tandem Mass Spectrometer (LC/MS). (P.I.: Ken Cornell) 7/2009 – 8/2012 NSF Co-P.I.; $597,877.
28. NSF Engineering Education Research to Practice (E2R2P). (Don Pumlee, Linda Huglin, Steve Villachica) 10/01/2010 – 9/30/2013, NSF, Sounding board member, $150,000.
29. MRI Acquisition of a tiled-display GPU/CPU cluster for Research and Education. NSF, (P.I. Inanc Senocak, Co-P.I. Julie Oxford, Peter Mullner, Tim Andersen, HP Marshall), 10/1/2012-9/30/2015, $555,384.
30. The Effects of Simulated Microgravity on Articular Cartilage—Travel Grant. College of Arts and Sciences, Boise State University; 2012, $800.
31. Boise State Research Vivarium Equipment. M.J. Murdock Charitable Trust; P.I.: Oxford, $248,000.
32. Induction of Early Stages of Osteoarthritis after Exposure to Microgravity (Postdoctoral Fellowship). 11/2011 – 10/2013, NASA National Space Biomedical Research Institute; Role on project: mentor; $100,000 for two years.
33. Extracellular Matrix is a Key Factor in Cancer Progression. M.J. Murdock Charitable Trust Partners in Science Program; Role on project: PI & Mentor, $15,000.
34. The effects of microgravity on cartilage health, 6/25/2011-6/24/2013; NASA Idaho Space Grant Consortium; P.I. Liliana Mellor, PhD; role on project Co-P.I./ Mentor, $50,000 for two years.
35. Regulation of cell signaling by Col11a1 during craniofacial development in the zebrafish. 09/01/09 – 08/31/13, NIH (NICHD), Role on project: P.I., $211,500.
36. Molecular Mechanisms of Cellular Mechanoreception in Bone. 9/1/2010 – 8/30/14, NASA, PI, $716,733.
37. Role of R-spondin1 to prevent joint damage after exposure to radiation and simulated microgravity. 1/1/14 – 12/31/14, Idaho Space Grant Consortium, P.I., $29,000.
38. Tertiary methacrylamides and thiourethane additives as novel dental composite restorative systems. (P.I. Carmem Pfeifer), 07/01/14 – 06/30/18, NIH/NIDCR, Collaborator, $54,002.
39. Clinical and Translational Research Infrastructure Network IDeA-CTR. (P.I. Langer) 7/1/13 – 6/30/18; NIH/NIGMS, ROLE ON PROJECT: Subaward P.I., $115,780.
40. Molecular Mechanisms of Inflammatory Cytokines in Bone Health. Jorcyk (P.I.), 01/01/14-09/01/15, FPK175-SB005, NASA EPSCoR Idaho Space Grant Consortium, Role: Collaborator, $30,000.
41. Role of Cellular Connectivity in Maintaining Osteogenesis Under Simulated Microgravity in Response to Mechanical Challenges. Uzer (P.I.), 04/15/17-04/30/18, FPK548-SB-008, National Aeronautics & Space Administration, Role: Co- P.I:, $30,000.
42. Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI TOF MS). Oxford (P.I.), 11/01/14-02/31/17, 2014092:MNL:11/20/2014, M.J. Murdock Charitable Trust, Role: P.I., $270,000.
43. COBRE Administrative Supplement for core consolidation. Oxford (PI), 6/1/17 – 5/31/18, NIH/NIGMS, Role: P.I., $300,000.
44. Hilda D. Elliott Foundation Fund; Osteoarthritis Research; $160,000.

Undergraduate Courses

Boise State University

• Biology/Materials Science/ Mechanical & Biomedical Engineering 477 Biomaterials Science
• Biology 497 Biochemistry of Cell Signaling Biology 497 Introduction to Bioinformatics Biology 191 General Biology
• Biology 493 Internship in Laboratory Research
• Biology 451 Developmental Biology, lecture and laboratory
• Biology 453 Advanced Developmental Biology
• Biology 301 Cell Biology
• Biology 202 General Zoology lecture and laboratory
• Chem 405 Research in Chemistry
• CID 200, 300, 400, 500 Vertically Integrated Projects –Plasma Medicine

Portland State University (adjunct professor)

• Chemistry 450 Biochemistry, 1991-1994.
• Chemistry 250 Nutrition, 1991.

Lewis and Clark College, Portland, Oregon (adjunct professor)

• Chemistry 335 and 336, Biochemistry lecture and laboratory, 1992.

Graduate Courses

Boise State University

• Biology/Materials Science/Mechanical & Biomedical Engineering 577 Biomaterials Science
• Biology 598 Biomaterials Graduate Seminar Biology 597 Biochemistry of Cell Signaling Biology 597 Introduction to Bioinformatics
• Biology 465/565 Advanced Topics in Molecular Biology Techniques Biology 466/566 Advanced Topics in Cancer and Developmental Biology Biology 567 Extracellular Matrix in Development and Disease
• Biology 596 Directed Research, Boise State University Biology 551 Developmental Biology, lecture and laboratory Biology 553 Advanced Developmental Biology
• Biology 650 Scientific Writing in the Biomedical Sciences
• BMOL 606 Scientific Proposal Writing
• GENCOUN 511 Developmental Anatomy and Embryology

Oregon Health Sciences University

• Oral Biology 513, Bone Physiology; endochondral and intramembranous ossification, 1998-2000.

Colorado State University (visiting professor)

• PS 796, Grant writing course, Department of Physiology, 1996.
• VS630, Molecular biology applications in Orthopaedic research, Veterinary Teaching Hospital, 1996.

Directed Research – Student Research Projects

Madyson McCartney 2019 – present

ApoE4 transport to the nucleus                                                                      

Conner Patricelli 2018 –  present

Role of ECM in cardiac mechanotransduction

Stephanie Frahs 2018 – present

Novel regulation of differentiation and mineralization in adult stem cells

Joe Christianson 2018 – present

Targeting LIFR signaling in cancer metastasis                                               

Roxanne Stone 2017 – present

Decellularized cartilage scaffold for stem cell differentiation and cartilage regeneration

Makenna Hardy 2017 –present

Role of minor fibrillar collagens in inner ear hair cell biomechanics

Kali Woods 2017 – 2020

Mechanisms of stem cell mechanotransduction

Jae Martini 2017 – 2019

Proteomic analysis of mitochondrial stress in fluoroquinolone-induced tendon damage

Aaron Sheetz 2016 – 2018

Mechanism of fluoroquinolone-induced tendon damage

Alexandria Hughes 2014 – 2015

ER stress and the Unfolded Protein Response in Stickler Syndrome type II

Began doctoral degree program at University of Colorado, 2015

Neda Shefa 2012 – 2015

BMP-2 and PTHrP in alternative splicing in skeletal development

Recipient of Sigma Xi Grant-in-aid-of-Research, 2013-2014

Began Medical School at University of Utah, 2015

Jonathon Reeck 2010 – 2017

Zebrafish model system for osteogenesis; cell polarity in chondrogenesis

Recipient of Sigma Xi Grant-in-aid of research, 2011

Ken Weekes 2013 – 2014

Characterization of a new adult stem cell line

Recipient of Sigma Xi Grant-in-aid-of-Research, 2013

Began Dental School/PhD program at OHSU in 2014

Hannah Parker 2013 – 2014

Extracellular Matrix in Breast Cancer Progression

First author publication on DiGeorge Syndrome

Began Medical School in 2014

Travis Baker 2013 – 2014

Mechanotransduction in bone and cartilage cells

Contributing author on publication

Began Medical School in 2014

Other: Item Writer for Medical College Admission Test, American College Testing Program, 1989-2009.

Invited Lectures and Presentations: > 70 presentations from 1983 – present; available upon request Contributed papers and posters at professional meetings: > 250 conference papers and posters from 1990 to present; available upon request